It seems to me that this indeed can be done with nexrender. However, most likely you would need a small team of an After Effects template designer, and a junior/middle javascript developer and about 20-40 hours to pull it off.
After that, in theory, you can just take existing template and infrastructure, feed it with needed data, including voice synthesized with a different library (it would be the developer's responsibility to find a fitting one), and generate as many total videos as you would need.
Server machine allocations are not handled. Nexrender can be used in 2 ways:
1. Direct binary form. (creating a start script for a newly launched machine taht will start predefined executable for example)
2. As a custom runtime. Creating a custom executable using nodejs that uses the nexrender as a kind of library, while you handle more high level stuff regarding
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Never heard about OpenCue up to this point, so can't tell you for sure if there is any direct way to implement integration, but I guess theoretically should not be that complicated :)
You can customize pretty much any After Effect layer properties, including font, text, colors, etc. So if I understood your question correctly, yeah you can. Regarding freelancers, any Javascript developer should do just fine.
After that, in theory, you can just take existing template and infrastructure, feed it with needed data, including voice synthesized with a different library (it would be the developer's responsibility to find a fitting one), and generate as many total videos as you would need.