By the way, OpenType.js has problems with parsing many fonts (old structures of TTF tables) and also with rendering some OTF (CCF) glyphs. If you are looking for a more versatile library, I recommend using Typr.js https://github.com/photopea/Typr.js
You mean writing a font back into a font file? Yes, this feature is not available now.
OpenType.js throws errors for many font files. It supports just a specific subset of standard font structures. It also renders some glyphs incorrectly. Typr.js does not have these problems (at least not during my testing).