The abundance of startup jobs and VCs in Silicon Valley is not matched anywhere else, and this makes quitting a stable job and working for a startup / starting a company a far less risky proposition than if you lived in an area where there were maybe 1-2 startups big enough to hire reliably. In those places people just don't make careers of working in startups because there aren't enough jobs / funding
That said, there are a lot of complicated industries where domain expertise trumps tech ability (healthcare is a prime example). Most successful health tech companies are not in CA (epic in Madison and cerner in Kansas City as two big examples). As more people learn to code I think there will be a growth in startups with relatively simple tech that is just well suited for the problem it addresses. Solutions that don't scale to millions of users / are not optimally performant but are designed by users can win in a lot of sectors
That said, there are a lot of complicated industries where domain expertise trumps tech ability (healthcare is a prime example). Most successful health tech companies are not in CA (epic in Madison and cerner in Kansas City as two big examples). As more people learn to code I think there will be a growth in startups with relatively simple tech that is just well suited for the problem it addresses. Solutions that don't scale to millions of users / are not optimally performant but are designed by users can win in a lot of sectors