These days, it's a good idea to test your site with AdBlock the same way you test it with multiple browsers. When a page appears to be broken the first thing I try is temporarily disabling AdBlock; the second thing is loading it in IE.
It does suck that you have to jump through these hoops because flagrantly intrusive ads have poisoned the well for innocent site-owners. I wish it were otherwise.
We have a file called that which has nothing to do with showing ads. If that's correct it will effectively break the service for anyone using AdBlock.